2,4-Dimethoxyacetophenone CAS 829-20-9 – High-Purity White Crystalline Ketone for API, Flavor

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2,4-Dimethoxyacetophenone (CAS Number 829-20-9) is a high-purity aromatic ketone featuring two methoxy groups on the benzene ring at the 2- and 4-positions. This compound is widely used as a synthetic intermediate in the pharmaceutical, agrochemical, fragrance, and material science industries. It appears as a white crystalline powder and is available in purity ≥99.0%, ensuring consistent quality and excellent compatibility with a wide range of organic reactions.

With a molecular formula of C10H12O3, 2,4-Dimethoxyacetophenone offers a balance of chemical reactivity, solubility, and thermal stability, making it ideal for advanced chemical synthesis and functional material development.

Item	Specification
Product Name	2,4-Dimethoxyacetophenone
CAS Number	829-20-9
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Appearance	White crystalline powder
Purity (by GC or HPLC)	≥99.0%
Melting Point	58 – 61 °C
Boiling Point	~296 °C
Solubility	Soluble in ethanol, methanol, chloroform
Moisture (Loss on Drying)	≤0.50%
Storage Temperature	Room temperature (sealed, dry condition)
Packaging	1kg 25kg/drum
Brand	Epoch

COA

Parameter	Specification	Test Method
CAS Number	829-20-9	N/A
Chemical Formula	C₁₀H₁₂O₃	Elemental Analysis
Molecular Weight	180.20 g mol⁻¹	Calculated
Appearance	White crystalline powder	Visual
Purity (GC)	≥99.0 %	Internal GC-FID
Loss on Drying	≤0.30 %	Karl Fischer
Melting Point	80–83 °C	USP <741>
Residue on Ignition	≤0.10 %	USP <281>
Heavy Metals (as Pb)	≤10 ppm	ICP-MS

Applications of 2,4-Dimethoxyacetophenone

2,4-Dimethoxyacetophenone is a highly versatile intermediate that plays a critical role in the synthesis of a wide array of fine chemicals and complex organic compounds.

Pharmaceutical Intermediates

Commonly used in the production of CNS-active drugs, anti-inflammatory agents, and analgesics.

Ideal for synthesizing heterocycles, aromatic esters, and bioactive benzyl compounds.

Offers a methoxy-rich core for structure–activity relationship (SAR) studies in drug discovery.

Fragrance and Flavor Industry

A precursor for ingredients with sweet, balsamic, or vanilla-like aromatic notes.

Enhances the aromatic intensity of perfumes and fine fragrances.

Agrochemical Synthesis

Used in the development of herbicides, plant growth regulators, and insect attractants.

Contributes to enhanced compound stability and biological activity in target molecules.

Organic Materials & Polymers

Intermediate in the design of specialty monomers and aromatic-based polymers.