2,5-Dimethoxyacetophenone CAS 1201-38-3 – Ultra-Pure Liquid Ketal for Pharmaceutical, Agro & OLED Innovations

Short Description:

2,5-Dimethoxyacetophenone (systematic name 1-(2,5-dimethoxyphenyl)ethan-1-one, CAS 1201-38-3) is a colorless to light-yellow transparent liquid with a guaranteed purity of 99.50 % min (GC) and moisture ≤0.20 % (Karl Fischer).

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Product introduction

2,5-Dimethoxyacetophenone is a high-quality aromatic ketone compound featuring two methoxy groups positioned at the 2- and 5-positions on the benzene ring, making it a valuable intermediate in pharmaceuticals, flavor & fragrance formulations, and advanced organic synthesis. This compound appears as a light yellow to colorless transparent liquid with a moisture content of ≤0.20% and a minimum purity of 99.50%, ensuring exceptional stability and consistency for both lab-scale and industrial applications.

Its well-balanced reactivity, excellent solubility, and clean spectral profile make 2,5-Dimethoxyacetophenone a sought-after compound in industries focused on fine chemicals, research development, and specialty product formulations.

Item	Specification
Product Name	2,5-Dimethoxyacetophenone
CAS Number	1201-38-3
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Appearance	Light yellow to colorless transparent liquid
Purity (GC)	≥99.50%
Moisture Content (KF)	≤0.20%
Boiling Point	Approx. 290 °C
Flash Point	~135 °C
Solubility	Soluble in ethanol, methanol, ether
Density (20°C)	~1.12 g/cm³
Refractive Index (n20/D)	1.520–1.526
Packaging	1kg
Storage Conditions	Store in a cool, dry place; sealed tightly

COA

Parameter	Specification	Test Method
CAS Number	1201-38-3	N/A
Chemical Formula	C₁₀H₁₂O₃	Elemental Analysis
Molecular Weight	180.20 g mol⁻¹	Calculated
Appearance	Colorless to light-yellow transparent liquid	Visual
Purity (GC)	≥99.50 %	Internal GC-FID
Moisture (KF)	≤0.20 %	Karl Fischer
Refractive Index (20 °C)	1.537 ± 0.003	ASTM D1218
Density (20 °C)	1.139 ± 0.005 g cm⁻³	ASTM D4052
Heavy Metals (as Pb)	≤5 ppm	ICP-MS
Infrared Identity	Conforms to reference spectrum	FT-IR

Applications of 2,5-Dimethoxyacetophenone

This compound is known for its excellent reactivity and chemical versatility, making it applicable across a range of synthesis environments and industries.

Pharmaceutical Industry

Used as an intermediate for API (Active Pharmaceutical Ingredient) synthesis.

Plays a role in the preparation of methoxy-substituted phenyl compounds with therapeutic potential.

Suitable for CNS-related drug research and complex heterocyclic compounds.

Fragrance and Flavor Chemistry

Useful in the development of aromatic aldehydes, esters, and sweet balsamic notes.

Acts as a key intermediate in producing musk-like and amber fragrance bases.

Fine Chemical Synthesis

Participates in Friedel–Crafts reactions, nucleophilic substitutions, and oxidative coupling.

Valuable in creating custom intermediates for electronic materials, dyes, and agrochemicals.

R&D and Specialty Materials

Frequently used in academic research projects to develop novel materials and functionalized organic scaffolds.