4-n-Butylacetophenone (CAS 37920-25-5) – 99.0 % min High-Purity Ketone for Pharma, Flavor

4-n-Butylacetophenone (CAS 37920-25-5) – 99.0 % min High-Purity Ketone for Pharma, Flavor Featured Image
  • 4-n-Butylacetophenone (CAS 37920-25-5) – 99.0 % min High-Purity Ketone for Pharma, Flavor

Short Description:

4-n-Butylacetophenone, catalogued under CAS 37920-25-5, is a clear to pale-yellow liquid ketone with ≥99.0 % GC purity. Its linear n-butyl chain grants exceptional lipophilicity and thermal stability, making it the preferred intermediate for NSAID synthesis, flavor & fragrance creation, and polymer additive R&D


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Product introduction:

4-n-Butylacetophenone is a high-quality aromatic ketone compound with a butyl group positioned on the para position of the benzene ring. This molecular configuration gives it excellent chemical stability and reactivity, making it a valuable intermediate in the pharmaceutical, flavor & fragrance, and fine chemical industries.

With a minimum purity of 99.0%, our 4-n-Butylacetophenone offers reliable performance, low impurity levels, and batch-to-batch consistency. The compound is produced under strict quality control systems to meet the demanding requirements of industrial and laboratory applications.

Item Specification
Product Name 4-n-Butylacetophenone
CAS Number 37920-25-5
Purity ≥ 99.0%
Appearance Colorless to pale yellow liquid
Molecular Formula C12H16O
Molecular Weight 176.26 g/mol
Boiling Point Approx. 280°C
Density 0.96 g/cm³
Storage Keep in a cool, dry, and well-ventilated environment
Packaging 200L/drumsSealed containers; customizable according to needs
Brand Epoch

 

COA

Parameter Specification Test Method Advantages for End-Users
Chemical Name 4-n-Butylacetophenone IUPAC nomenclature Exact structure, no branched isomers
CAS Number 37920-25-5 CAS Registry Global harmonized identifier
Purity (GC) ≥99.0 % GC-FID High conversion, minimal work-up
Appearance (25 °C) Clear to pale-yellow liquid Visual Easy visual QC at receiving dock
Moisture ≤0.2 % Karl Fischer Inhibits hydrolysis side-reactions
Color (APHA) ≤50 ASTM D1209 Suitable for color-sensitive formulations
Molecular Formula C₁₂H₁₆O Elemental analysis Matches stoichiometric requirements
Molecular Weight 176.25 g mol⁻¹ Calculated Precise molar dosing
Density @ 20 °C 0.952–0.958 g cm⁻³ ASTM D4052 Accurate volumetric dispensing
Refractive Index 1.510–1.514 ASTM D1218 Quick purity check on-line
Boiling Point 260–262 °C @ 760 mmHg DSC Compatible with high-temp reactions
Flash Point >110 °C (CC) ASTM D56 Safer handling & shipping classification

 

 Application of 4-n-butylacetophenone

4-n-Butylacetophenone is a versatile intermediate used in various industries:

Pharmaceutical API: It is an intermediate in the synthesis of cannabinoid-2 agonists and COX inhibitors and plays a vital role in the development of therapeutic agents.

 Fragrances and Fragrances: This compound acts as a precursor to musk ketone, enhancing the woody amber notes in fragrance formulations and helping to improve the overall scent and stability of the product.

Electronic Chemicals: In electronics, it is used as a dopant in the charge transport layer of organic light-emitting diodes (OLEDs), improving device performance.

 Agrichemicals: 4-n-Butylacetophenone is used in the synthesis of herbicide safeners, which help protect crops from the harmful effects of herbicides.

Polymer additive: Used to create UV-absorbing benzophenone grafts, enhancing the stability and lifespan of polymer products exposed to UV radiation.

 

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