4-Phenoxy-2′,2′-dichloroacetophenone | CAS 59867-68-4 | 99.5 % White Powder

4-Phenoxy-2′,2′-dichloroacetophenone | CAS 59867-68-4 | 99.5 % White Powder Featured Image
  • 4-Phenoxy-2′,2′-dichloroacetophenone | CAS 59867-68-4 | 99.5 % White Powder

Short Description:

4-Phenoxy-2′,2′-dichloroacetophenone (CAS 59867-68-4) is a bright white, free-flowing crystalline powder with an assay ≥99.5 % (GC). The strategic placement of a phenoxy spacer and geminal dichloroacetyl group imparts electrophilic selectivity, UV stability, and bioactivity synergy, positioning the molecule as the preferred building block for pyrethroid insecticides, antifungal APIs, and high-performance UV-absorber additives


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Product introduction

4-Phenoxy-2′,2′-dichloroacetophenone is a premium-grade aromatic ketone compound that contains both a phenoxy group and dichloroacetophenone moiety. This structural combination offers unique reactivity and stability, making it a valuable intermediate in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing.

Produced through advanced synthesis technology, our 4-Phenoxy-2′,2′-dichloroacetophenone meets 99.5% purity standards, ensuring minimal impurities and excellent batch-to-batch consistency. It is supplied as a white crystalline powder with excellent handling and storage stability, making it ideal for both laboratory and industrial applications.

Item Specification
Product Name 4-Phenoxy-2′,2′-dichloroacetophenone
CAS Number 59867-68-4
Appearance White crystalline powder
Purity ≥ 99.5%
Molecular Formula C₁₄H₁₀Cl₂O₂
Molecular Weight 297.13 g/mol
Melting Point 84 – 87°C
Boiling Point Approx. 390°C
Storage Store in a cool, dry, and well-ventilated environment
Packaging 25kg/drums Sealed bags, fiber drums, or customized packaging
Brand Epoch

 

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Parameter Specification Method Competitive Edge
Chemical Name 4-Phenoxy-2′,2′-dichloroacetophenone IUPAC Exact connectivity, no isomeric mixtures
CAS Number 59867-68-4 CAS Registry Global traceability
Appearance White crystalline powder Visual (25 °C) Low color, easy QC by eye
Purity (GC) ≥99.5 % GC-FID Reduces downstream purification
Moisture (KF) ≤0.2 % Karl Fischer Prevents hydrolysis of acid chloride handle
Melting Point 118–122 °C DSC Sharp range confirms crystal phase purity
Molecular Formula C₁₄H₁₀Cl₂O₂ Elemental analysis Matches exact stoichiometry
Molecular Weight 281.14 g mol⁻¹ Calculated Precise molar dosing
Particle Size D90 ≤75 µm (micronized) Laser diffraction Excellent flow & dissolution
Loss on Drying ≤0.3 % USP <731> Minimal volatile impurities
Residue on Ignition ≤0.1 % USP <281> Ultra-low ash for electronics
Heavy Metals ≤5 ppm total (ICP-MS) ICP-MS Meets USP<232

 

Applications of 4-Phenoxy-2′,2′-dichloroacetophenone 

4-Phenoxy-2′,2′-dichloroacetophenone  is an important intermediate with a wide range of applications in various industries:

Pharmaceutical Industry: It is used in the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules as scaffolds for azole antifungal drugs such as voriconazole.

Agrochemical Industry: This compound can be used as a precursor in the development of crop protection agents, including herbicides and insecticides, in particular as an intermediate for deltamethrin analogs in pyrethroid insecticides.

Specialty Chemicals: It is used to create high-performance chemical compounds for specific applications, including as a precursor to benzophenone-4 derivatives in UV additive formulations.

Research and Development: 4-Phenoxy-2’,2’-dichloroacetophenone is used in synthetic chemistry projects and laboratory-scale reaction studies, promoting advancements in various areas of chemical research.

Electrophotography: It acts as a charge control agent in toner resins, enhancing the performance of electrophotographic materials.

Custom Synthesis: This compound is also used in a variety of custom synthesis applications, including Friedel-Crafts and Grignard reactions, enabling the creation of complex organic structures.

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